A new analysis technique The team developed a method dubbed Computational Immune Synapse Analysis (CISA) which detects not only which cells within a tissue contact each other physically ...

When naive T cells encounter antigen-presenting cells (APCs), membrane and cytoplasmic molecules rearrange at the T cell–APC contact area to form the immune synapse. Finetti et al. now reveal an ...

The CD2-CD58 axis is associated with the regulation of autoimmune diseases, immune evasion of tumors, antiviral responses, and immune rejection, and targeted therapies for this have been developed.

A new analysis technique The team developed a method dubbed Computational Immune Synapse Analysis (CISA) which detects not only which cells within a tissue contact each other physically ...

The interaction between CD2 and CD58 is critical for forming the immunological synapse, which is pivotal in immune cell activation and adhesion, as well as signaling in both immune and target cells.

The team developed a method dubbed Computational Immune Synapse Analysis (CISA) which detects not only which cells within a tissue contact each other physically, but also whether key molecules are ...

Killer lymphocytes destruction of infected or transformed target cells: Cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells play a central role in immune responses against intracellular ...