Here, we discuss strategies to select the best therapeutic antigen targets, to optimize the structure of IgG antibodies and to design related or new structures with additional functions.

The properties of the different IgG isotypes should be considered in developing therapeutic antibodies ... IgG4 designed to further reduce effector functions. Moreover, IgG4-PE had the additional ...

IgG, the most prevalent antibody in our bloodstream, can neutralize toxins, viruses, and bacteria. This recent study delved into the effects of aging on tissue integrity and organ function. The ...

and cells with specific structures and functions are the main components of the SSS microenvironment. The expression of ...

Nipocalimab was well-tolerated over the six-month study period, with no major safety signals observed. The most common adverse events (AEs) were infections and infestations: 60.4% (n=32) in the ...