The retroviral replication cycle requires that retroviral nucleic ... In contrast, lentiviruses such as human immunodeficiency virus (HIV) do not depend on host cell mitosis to access the nucleus.

For this purpose, anti-HIV drugs target essential viral proteins in the replication cycle of HIV, mostly the viral reverse transcriptase and protease. Unfortunately, HIV is highly variable and ...

Once inside the body, HIV persists because of its remarkable ability to hide within healthy CD4 T cells, where it can lie ...

Schulich School of Medicine & Dentistry researchers are on the cutting-edge of the study of HIV, working toward treatments ...

They graphically represent the life cycle of HIV-1, from the initial binding of the viral particle onto a host cell (Viral Entry), through insinuation into the host cell's nucleus to spark the ...

A new rule from the Biden administration allows organ transplants from HIV-positive donors to HIV-positive recipients.