This study revealed a new pathway for stress-induced glucose release, providing critical insights into glucose homeostasis and potential therapeutic targets for stress-related metabolic disorders.
via glucose autoxidation, and via hexosamine metabolism under supraphysiological glucose concentrations, we hypothesize that chronic oxidative stress is an important mechanism for glucose toxicity.
The purine/purinergic system has emerged as a fundamental regulator of cellular communication, influencing various physiological processes such as metabolism, energy balance, and signal transduction.
Clear cell renal cell carcinoma (ccRCC) is notably characterized by abnormal lipid and glucose metabolism, which not only perturbs the cellular energetics but also impacts the surrounding tumor ...