The idea that speckles might be storage sites for spliceosomes triggered Guttman to look deeper into how nuclear organization ...

Researchers at the Centre for Genomic Regulation (CRG) in Barcelona have created the first blueprint of the human spliceosome ...

A new study helps explain the role of genetic variation in shaping gene regulation in the Indonesian archipelago, one of the most diverse regions in the world. “This study is the only study of ...

The study, published this week in Nature Genetics, shows that the biggest impact of alternative splicing may come via its role in regulating gene expression levels. The research team, led by Yang ...

Detailed map of the spliceosome is being made publicly available to help researchers pinpoint exactly where splicing errors ...

This produces the mature mRNA that contains the instructions for making a protein for a specific gene. Because incorrect RNA splicing can result in dysfunctional or overactive proteins ...