After a decade of work, scientists have completed a molecular model of the human spliceosome, an incredibly complex cellular ...

RNA可变剪接 (Alternative ...

The idea that speckles might be storage sites for spliceosomes triggered Guttman to look deeper into how nuclear organization ...

Detailed map of the spliceosome is being made publicly available to help researchers pinpoint exactly where splicing errors ...

Researchers have created the first blueprint of the human spliceosome, the most complex and intricate molecular machine in human biology. The vast majority of human genes -- more than nine in ten -- ...

A new proof-of-concept method reliably engineered a hotspot mutation of SF3B1, a gene-splicing gene, into diverse cancer cell lines, outperforming other contemporary editing approaches.

The spliceosome edits genetic messages transcribed from DNA, allowing cells to create different versions of a protein from a single gene. The vast majority of human genes – more than nine in ten ...

Hardly a day goes by that there isn’t scientific news somewhere about a new advancement in genetic manipulation. For instance ...

A new mouse model mimicking the liver symptoms of myotonic dystrophy type 1—the most prevalent form of adult-onset muscular ...