First, they must enter the host cells, which RSV does using its fusion (F) protein. Vaccines induce antibodies that bind to pathogens. Neutralizing antibodies bind to crucial sites, such as part ...
Subscribe for FREE Scientists have long attempted to create vaccines that coax the immune system into recognizing the fusion (F) proteins present on the surfaces of RSV, hMPV and related viruses.
Scientists have long attempted to create vaccines that coax the immune system into recognizing the fusion (F) proteins present on the surfaces of RSV, hMPV and related viruses. These proteins play ...
This is the RSV fusion glycoprotein is shown (left) in its pre-fusion state in complex with an antibody (red and white ribbon) and (right) in its post-fusion shape. Disclaimer: AAAS and EurekAlert!
Most assays target the RSV fusion surface glycoprotein. The color change is mediated by the binding of viral protein from the sample to the test's RSV-specific antibodies. The apparatus ...
RSV F proteins sit on the viral surface, ready to engage with host cell receptors and regulate the virus's fusion and entry into the host cell. The scientists' images reveal that in RSV ...