Objective: In order to assess the long-term (12 months) efficacy and safety of fenofibrate ... above 300 mg/dL and low-density lipoprotein cholesterol (LDL-C) was over 160 mg/dL after at least ...

All participants received simvastatin and also were assigned to daily fenofibrate (160 mg) or placebo. Mean follow-up was 4.7 years. In both groups, mean LDL levels dropped from ≈100 mg/dL to ...