Dysregulation of F-actin can lead to changes in cell shapes and biomechanics, which can contribute to a range of diseases including blood disorders, immunodeficiencies, muscle myopathies, cataracts, ...

Methods: Serum samples were obtained from 33 healthy controls and 33 patients with severe skeletal muscle damage, defined by a total creatine kinase value of >500 IU/l (Rosalki method). Troponin I, ...

The new study shows that preventing F-actin accumulation led to much more active autophagy in the brains of aged fruit flies. The authors found that if they removed F-actin but also disabled ...