ACE inhibition is a sufficiently well accepted treatment modality, and most of the guidelines addressing treatment of hypertension, renal disease, and/or cardiovascular disease have this ...

Small-molecule enzyme-inhibitors often display insufficient affinity and selectivity for their targets causing unwanted side effects when used as drugs. Molecularly imprinted polymers prepared ...

11) and our understanding of ACE made a compelling argument for a new attempt at designing small molecular weight inhibitors. We had at our disposal not only an enzyme assay but also a highly ...

Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Center have achieved a breakthrough ...

In mice, inhibiting protein S-palmitoylation Counteracted accumulation of harmful proteins in neurons and delayed onset and progression of cognitive decline.

A potential new treatment for Alzheimer’s disease may come in the form of a nasal spray. Researchers in Italy have discovered ...

An enzyme called EZH2 has an unexpected role in driving aggressive tumor growth in treatment-resistant prostate cancers, ...

A future treatment for Alzheimer disease may involve a nasal spray. Researchers at Università Cattolica and Fondazione ...

An enzyme called EZH2 has an unexpected role in driving aggressive tumor growth in treatment-resistant prostate cancers, ...

Proton pump inhibitors are a class of medications used to treat conditions like GERD and ulcers. They work by blocking the ...

Researchers revealed new details of DNA gyrase, using high-resolution cryo-electron microscopy, paving the way for more ...

An enzyme called EZH2 has an unexpected role in driving aggressive tumor growth in ... of a protein called PKCλ/ι in prostate cancer cells enables EZH2 to drive aggressive growth, even with androgen ...