基于该方法，研究团队首次设计出了在超过10亿年分化物种（包括哺乳动物、鸟类、鱼类、昆虫和酵母等）中具有保守功能的增强子序列，揭示了增强子调控语法的跨物种保守性。此外，设计出的超强增强子活性显著高于不同物种中常用的最强增强子，同时也首次设计出了基因表达 ...

During transcription, proteins bind to sequences of DNA, such as promoters and enhancers, inside the cell to directly impact ...

Within all cells, including T cells, there are regions of DNA called "enhancers." This DNA does not code for proteins.

Researchers discovered that gene deserts, non-coding DNA regions, regulate heart and embryo development through enhancer ...