Further analysis using advanced electron microscopy revealed that a specific subset of IP3 receptors, particularly those located near desmosomes, plays a key role in CaRE. Desmosomes are cell adhesion ...
Further analysis using advanced electron microscopy revealed that a specific subset of IP3 receptors, particularly those located near desmosomes, plays a key role in CaRE. Desmosomes are cell ...
Intercellular adhesion can be mediated by adherens junctions, tight junctions and desmosomes, whereas cells can interact with extracellular matrix molecules through focal adhesions. Talin controls ...
Adherens junctions (red dots) join the actin filaments of neighboring cells together. Desmosomes are even stronger connections that join the intermediate filaments of neighboring cells.
Further analysis using advanced electron microscopy revealed that a specific subset of IP3 receptors, particularly those located near desmosomes, plays a key role in CaRE. Desmosomes are cell ...
Pemphigus is an autoimmune bullous disease, in which autoantibodies react with the cell–cell adhesion structures, desmosomes, causing blisters and erosions on the oral mucosa and skin.
With mutated desmosomes, normal levels of myocardial wall stress lead to cellular disruption and (fibro-fatty) repair, ending in familial ARVC. But we propose that a similar phenotype may develop when ...
Pemphigus is a rare autoimmune blistering disease involving the skin and mucous epithelia. It is clinically characterized by flaccid blisters and erosions (Figure 1) and, if left untreated, could ...