Adenylyl cyclase creates multiple cyclic AMP molecules, which fan out and activate protein kinases (PKA, in this example). Protein kinases can enter the nucleus and affect transcription.

With its selection of kits (cAMP femto, cAMP dynamic and cAMP HiRange), Cisbio allows detection of a broad range of cyclic AMP concentrations. Classically, the GPCR signaling pathway is considered ...