One of the authors, Dalia Smalakytė, points out that the activity of the CRISPR-Cas protein scissors is tightly regulated in ...

This protein can easily be programmed to find ... So why do we call it CRISPR? Cas proteins are used by bacteria to destroy viral DNA. They add bits of viral DNA to their own genome to guide ...

In recent years, scientists have created a range of new methods based on CRISPR-Cas technology for precisely editing the ...

Researchers at ETH Zurich combined two CRISPR-Cas methods to decipher how mutations in a cell’s genome affect its function.

One of the authors, Dalia Smalakytė, points out that the activity of the CRISPR-Cas 'protein scissors' is tightly regulated ...

"It's a completely brand-new type of CRISPR chemistry," says co-first author Christian Baca, a TPCB graduate student in the Marraffini lab. "It's more evidence that CRISPR systems have an array of ...

for example a protein or nucleic acid. Prokaryotic CRISPR–Cas systems are counteracted by phage-encoded anti-CRISPR elements, and how they protect themselves remains enigmatic. A study shows ...

Cas9, cuts any RNA or DNA it recognizes as foreign, and thereby protects bacteria from viral attacks. Another CRISPR system, one that is relatively obscure, protects bacteria in an entirely different ...

In addition, research is focused on protein-RNA complexes mediating the piRNA pathway ... Phage-encoded anti-CRISPR enables full escape from type VIA CRISPR-Cas immunity. Science 369, 54-59. Li, W., ...