Using state-of-the-art technology, researchers have identified several specific steps needed for CRISPR to become active and perform its gene editing function. These preclinical findings could lead to ...

CRISPR/Cas9 is a gene editing tool that has revolutionized biomedical research and led to the first FDA-approved CRISPR-based gene therapy. However, until now, the precise mechanism of exactly how ...

"It's a completely brand-new type of CRISPR chemistry," says co-first author Christian Baca, a TPCB graduate student in the Marraffini lab. "It's more evidence that CRISPR systems have an array of ...

Cas9, cuts any RNA or DNA it recognizes as foreign, and thereby protects bacteria from viral attacks. Another CRISPR system, one that is relatively obscure, protects bacteria in an entirely different ...

Today’s mass-produced tomatoes often grow to palm-sized proportions, but their naturally occurring ancestors were far smaller ...

Researchers discovered that the CRISPR-Cas10 system not only cuts viral DNA but also produces toxic cyclic-oligoadenylates ...

Crispr has already secured a historic first approval for a CRISPR/Cas9 drug and has several more potential blockbuster ...

Originally discovered in bacteria as a defense mechanism against pathogens, CRISP/Cas9 has made it possible to make exquisitely detailed and precise alterations to DNA sequences on demand ...

These proteins use different mechanisms to inhibit the recognition ... it can inhibit the cleavage activity of the host CRISPR-Cas9 system, thereby protecting the bacteriophage genome from ...

CRISPR/Cas9 is a gene editing tool that has revolutionized biomedical research and led to the first FDA-approved CRISPR-based ...