CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...
Genome editing technologies, particularly CRISPR/Cas9, have garnered widespread attention for their potential to make precise changes to the genetic material of organisms. This has paved the way for ...
This study presents important findings on cold tolerance shared between hibernating and non-hibernating mammals, identifying a key molecule, GPX4, through multi-species genome-wide CRISPR screens. The ...
1 However, this genome editing staple still has its limitations ... In its unaltered state, the editing efficiency of TnpB is between zero and 20 percent, which is lower than that of the smallest ...