*仅供医学专业人士阅读参考虽然CD8+T细胞毫无疑问是抗肿瘤免疫应答的主导者，但看过这么多研究的大家想必也都明白，它们“能不能C”往往要看其它各方面给不给面子，像是CD4+T细胞当中的调节性T细胞（Tregs）就经常去当免疫抑制的反派角色，搞得奇点糕 ...

After being activated, T lymphocytes must consume fuel for energy and biomaterials to sustain rapid proliferation and differentiation ... how activated CD8 + effector T cells handle ammonia ...

Researchers from the Josep Carreras Leukaemia Research Institute have found that the efficacy of varni-cel, a CAR-T infusion product for B-ALL patients, is highly dependent on intrinsic features of ...

To examine the Mettl3-dependent epi-transcriptional regulation in effector CD8 T cells, this study combined transcriptome and m 6 A modification abundance analysis of effector CD8 T cells. The ...

PHILADELPHIA, PA — Century Therapeutics (NASDAQ: IPSC) is set to showcase groundbreaking advancements in its iPSC-derived ...

A study highlights that the efficacy of varni-cel, a CAR-T therapy for B-ALL, hinges on three key markers: CD4 ratio, exhaustion signals and gamma-delta T-cell expansion. This research may enhance ...

T cells are separated according to CD4 and CD8 expression into cytotoxic T cells (CD3+CD8+) and helper T cells (CD3+CD4+). PBMCs are critical in research and clinical settings. They function as a ...

Company to share preclinical data across diverse pipeline of iNK, γδ iT, and αβ iT cell therapy programs for oncology and autoimmune disease ...