A mutation in the BAX gene, however, commonly found in high-frequency microsatellite instability tumors, could have a role in TRAIL sensitivity and affect the potential use of TRAIL-receptor agonists.
Usually localized in the cytosol, Bax translocates to the mitochondrial membrane during induction of apoptosis in thymocytes, or in cells treated with staurosporin. [30,31] Mutation analysis has ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback