A mutation in the BAX gene, however, commonly found in high-frequency microsatellite instability tumors, could have a role in TRAIL sensitivity and affect the potential use of TRAIL-receptor agonists.

Polymorphisms in upstream activators, repressors or downstream effectors of p53 might individually modulate cancer risk or interact with polymorphisms or mutations in TP53. Because the effects of ...

Applied since the 1930s to accelerate the process of developing and selecting new valuable agronomic traits, mutation breeding uses a plant’s own genetic make-up, mimicking the natural process of ...

Researchers discovered that mammals - from tigers to humans - have roughly the same number of mutations by the time they die of old age. But short-lived animals tend to burn through their ...

Usually localized in the cytosol, Bax translocates to the mitochondrial membrane during induction of apoptosis in thymocytes, or in cells treated with staurosporin. [30,31] Mutation analysis has ...

Hereditary breast cancer results from inherited mutations, primarily in BRCA1 and BRCA2, increasing lifetime cancer risk. Additional genes like TP53, PTEN, PALB2, CHEK2, and ATM also contribute to ...

Since the virus was first identified a year ago, thousands of mutations have arisen. The vast majority of mutations are "passengers" and will have little impact, says Dr Lucy van Dorp, an expert ...

Mutations occur continuously and can be spontaneous. Most are caused by errors when the DNA is copied prior to cell division. They can also happen because of: ionising radiation close ionising ...

We sell different types of products and services to both investment professionals and individual investors. These products and services are usually sold through license agreements or subscriptions ...

One company value investors might notice is Baxter International (BAX). BAX is currently sporting a Zacks Rank of #2 (Buy) and an A for Value. The stock has a Forward P/E ratio of 12.09.

We sell different types of products and services to both investment professionals and individual investors. These products and services are usually sold through license agreements or subscriptions ...

ZBHZimmer Biomet Holdings, Inc.