Nature2y
Autophagy: from phenomenology to molecular understanding in less than a decade
Time-lapse studies provide compelling images which suggest that autophagosome formation proceeds in a step-wise manner, marked by the expansion of the sequestering membrane 10 (Supplementary ...
Science Daily10d
Bulges calculated in the supercomputer: How cells digest their internal canal system
Inside cells, there exists an extensive system of canals known as the endoplasmic reticulum (ER), which consists of membrane-encased tubes that are partially broken down as needed -- for instance in ...
Nature2y
Focusing on Autophagy
Starvation conditions were later shown to enhance the formation of such vesicles, whereas amino acids, the end products of this degradative process, inhibit their formation. So, it appeared that ...
Computer simulations reveal how cells break down the endoplasmic reticulum
We were able to show that they do this during the formation of the bulges ... membrane pinches off and the vesicle is ...
Computer simulations reveal how cells break down the endoplasmic reticulum
Inside cells, there exists an extensive system of canals known as the endoplasmic reticulum (ER), which consists of membrane-encased tubes that are partially broken down as needed—for instance in case ...