Atherosclerosis involves multiple processes ... Here we will review the current understanding of the pathophysiological mechanisms and the status of molecular and gene therapeutic approaches ...

New discoveries in atherosclerosis pathways have shed light on the active mechanisms in other diseases such as chronic kidney disease (CKD) and HIV, paving the way for furture therapeutics.

In a new study published in the European Heart Journal, researchers at Karolinska Institutet show that genetic traits ...

We used this phenomenon to understand the biological mechanisms putting us at risk,” says senior ... finding that reducing ...

Dr. Hamczyk concluded, "This study describes new cellular and molecular mechanisms involved in atherosclerosis and proposes a ...

in atherosclerosis. Thus, we sought to comprehensively review the available data on the topic, exploring in particular the pathogenetic mechanisms, and discuss anticipated future directions.

Furthermore, the scientists showed that one amino acid—leucine—seems to have a disproportionate role in driving the ...

Here I discuss recent advances in the study of endoplasmic reticulum stress as one mechanism that links immune response with nutrient sensing in the pathogenesis of atherosclerosis and its ...

Cholesterol crystals (CCs) have a pathogenic role in various cardiovascular diseases, particularly atherosclerosis. In this Review, Boisvert and colleagues describe the mechanisms underlying CC ...

We have found a mechanism that explains how rapid laminar flow protects against endothelial leaks. The molecular basis of this mechanism revealed potential targets for reducing atherosclerosis.