The second analysis showed that while no specific antipsychotic offered greater cognitive benefit, first-generation dopamine ...

Negative data cost AbbVie billions of dollars in market value and convinced analysts Bristol Myers had placed a better bet in ...

Just as we got used to the idea that antipsychotic medications needed to block both dopamine and serotonin receptors, specifically the D-2 receptor and the 5HT-2A receptor, and these (somewhat ...

Insurer access challenges likely lie ahead for the novel schizophrenia drug Cobenfy, given its considerably higher price than ...

Extra firing (production of this neurotransmitter) of dopamine in these pathways produces many of the symptoms of schizophrenia. Many atypical or second generation antipsychotics block serotonin ...

Lyu X, Li Z, Chen S, et al. Transcranial direct current stimulation improves tardive dyskinesia in long-term hospitalized patients with chronic schizophrenia. Clin Neurophysiol. 2024;166:20-30. doi:10 ...

In fact, several antipsychotic drugs, grouped according to their receptor affinity, were associated with some benefit in a post-hoc analysis, with small effect sizes: Adrenergic/low dopamine ...

Antipsychotics—a branch of medication designed to treat schizophrenia and bipolar disorder—are important tools for mental health care management. They work by blocking the effect of dopamine, which ...

First-generation antipsychotics, such as haloperidol (0.04) and fluphenazine (0.15), ranked low in cognitive performance, as did clozapine, a second-generation antipsychotic often used for ...

New University of Pittsburgh research points to a potential approach to reducing the risk of diabetes associated with ...