Video: "The work that we do now impacts generations of cancer patients in the future." Watch Professors Udai Banerji and Ian Collins talk about their work on AKT inhibitors. AKT – which is also known ...

We also found that tumor growth induces overly activated regulatory T (Treg) cells with their CTL suppressor function titratable along the PI3K-Akt-Foxo1 signaling pathway to overcome cancer immune ...

AKT controls protein synthesis and oxidative metabolism via combined mTORC1 and FOXO1 signaling to govern muscle physiology. Journal of Cachexia, Sarcopenia and Muscle (2021). Impact 12.9 N Jaiswal, ...

FoxO1-GAB1 axis regulates homing capacity and tonic AKT activity in chronic lymphocytic leukemia ... Mechanisms and clinical activity of an EGFR and HER2 exon 20-selective kinase inhibitor in ...

Atavistik Bio Inc. has nominated an orally bioavailable selective allosteric AKT1 E17K inhibitor, ATV-1601, as a development candidate for AKT1 E17K-driven cancers.

Historically, most people started HIV treatment with two drugs from the NRTI class combined with either one NNRTI, one protease inhibitor or one integrase inhibitor – hence, ‘triple therapy’.

Pathway students benefit from language coursework carefully designed to help English language learners prepare for academic study. Pathway students also benefit from joining mainstream academic ...

ACE inhibitors are best known for treating high blood pressure. They work by targeting the hormone angiotensin II. Angiotensin-converting enzymes (ACE) inhibitors help blood vessels to relax and open.

The MSc Education (Open Pathway) allows you to design your own programme of study based on your areas of interest, rather than choosing one subject area from our specialist pathways. Units can be ...