(IGF1, insulin-like growth factor 1; MAPKAP-K1, mitogen-activated protein kinase (MAPK)-activated protein kinase 1; PDK1, 3-phosphoinositide-dependent protein kinase 1; PKB/AKT, protein kinase B ...

The results painted a rather different picture to that described above: IL-4, a good activator of PKB/Akt but not of mitogen-activated protein (MAP) kinase, failed to induce endogenous BAD ...

Metformin and GLP-1 receptor agonists significantly reduce asthma attacks in patients with type 2 diabetes, offering ...

MD Biopharm Co. Ltd. has identified compounds acting as mitogen-activated protein kinase kinase kinase 11 (MAP3K11; MLK3) and kinase 1 (MAP4K1; HPK1; MEKKK1) inhibitors reported to be useful for the ...

AKT signaling pathway is one of the most critical and extensively investigated signaling pathways. It is the central ...

(Alliance News) - Poolbeg Pharma PLC on Wednesday announced its immunomodulator I patent has been granted in the US. The London-based clinical stage biopharmaceutical company targeting diseases with a ...

Lafleur E, Kapfer C, Joly V, Liu Y, Tebbji F, Daigle C, Gray-Mitsumune M, Cappadocia M, Nantel A and Matton DP 2015. The FRK1 mitogen-activated protein kinase kinase kinase (MAPKKK) from Solanum ...