It has something to do with a sliding interaction between actin and myosin. In 1954, scientists published two groundbreaking papers describing the molecular basis of muscle contraction.

Methods: Serum samples were obtained from 33 healthy controls and 33 patients with severe skeletal muscle damage, defined by a total creatine kinase value of >500 IU/l (Rosalki method). Troponin I, ...

seen as a cross-bridge between actin and myosin filaments in muscle, acts as the motor domain of the molecule and pulls actin filaments along by repetitive conformational changes coupled to ATP ...

In the KEGG pathway database, changes in the expression of various actin–myosin filament component proteins and their regulatory proteins have also been implicated in various cardiac disease ...

Muscle fatigue,Facial weakness, Cardiac problems ... which produce proteins important for muscle function like skeletal a-actin (ACTA1) and nebulin (NEB) genes,” says Dr Annie Q Hasan, Sr ...

Our lab’s investigations of cardiac muscle contraction focus on the effects of cardiomyopathy-causing amino acid substitutions on myosin’s mechanical and enzymatic properties and tropomyosin’s ability ...

F-actin is a key regulator of cellular architecture and how appropriate cellular ... It is required for efficient muscle contraction in both skeletal and cardiac muscles. "I started with a molecule ...