For further analysis, we purified a fusion protein (limitin–Ig) prepared from limitin and human immunoglobulin (Ig) from the supernatant of 293T cells transfected with the limitin–Ig/BOS plasmid.
Further, in a mouse model of TEN, oral administration of tofacitinib, or the JAK1 and JAK2 inhibitor baricitinib, reduced STAT1 phosphorylation and disease severity, decreased keratinocyte death ...